Conformational ensembles
A collection of multiple low-energy conformations of a molecule, generated to represent its conformational flexibility.
Intrinsically disordered protein (IDP)
A protein that lacks a single, stable 3D structure under physiological conditions, instead existing as a dynamic ensemble of different conformations.
Intrinsically disordered region (IDR)
A part of a protein that lacks a stable, fixed three-dimensional structure.
Structural state
A structural property that a protein region can exhibit, defined by its conformational behavior under physiological conditions.
Structural transition
A dynamic process in which a protein region undergoes a reversible or irreversible transformation between defined and undefined structural states.
Database
An organized collection of data, stored and managed in a structured way, that allows efficient access, retrieval, and analysis of information. In the life sciences, store biological, structural, or experimental data to support research and knowledge sharing.
DIBS (Database of Disordered Binding Sites)
Is a repository for protein complexes that are formed between intrinsically disordered proteins and globular/ordered partner proteins.
DisProt
Major manually curated repository of intrinsically disordered proteins, both for structural and functional aspects.
ELM (Eukaryotic Linear Motif)
Annotation and detection of eukaryotic linear motifs by providing both a repository of annotated motif data and an exploratory tool for motif prediction.
MobiDB
The unique database that integrates information on protein intrinsic disorder and related structural features, combining experimental annotations with computational predictions.
PED (Protein Ensemble Database)
A database that collects, and provides access to structural ensembles of intrinsically disordered proteins, representing their conformational diversity.
Ontology
In information science, an ontology is a formal representation of knowledge within a domain that models concepts and their relationships to enable automated reasoning.
IDPO (Intrinsically Disordered Proteins Ontology)
A source of information on the IDRs/IDPs structural and functional properties.
FAIR principles
A set of guidelines for managing research data to make it more Findable, Accessible, Interoperable, and Reusable for both humans and machines
MIADE (Minimal Information About Disordered Experiment)
A standardized framework that provides guidelines for documenting the experimental data related to intrinsically disordered proteins.
OBO format
A plain-text, human-readable format for representing biological ontologies, designed to be easy to parse and extensible.
OWL format
A Semantic Web language designed to represent rich and complex knowledge about things, groups of things, and relations between things.